RecruitingNCT07492004

China Monogenic Diabetes Registry


Sponsor

Tianjin Medical University General Hospital

Enrollment

5,000 participants

Start Date

Feb 28, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

This observational study aims to establish a digital registry, screening platform for patients with monogenic diabetes using internet-based and mobile application technologies. The primary objectives are to: Characterize the genetic landscape of monogenic diabetes in the Chinese population, including pathogenic variants and their distribution Participants will: * Enroll in the monogenic diabetes registry via mobile application or web-based platform * Undergo molecular genetic testing to establish a definitive diagnosis


Eligibility

Inclusion Criteria3

  • Diabetes diagnosed before 25 years of age; OR diabetes diagnosed before 35 years of age with ≥1 first-degree relative (parent, sibling, or offspring) diagnosed with diabetes before 40 years of age
  • Body mass index (BMI) at diagnosis 28 kg/m²
  • Negative glutamic acid decarboxylase antibody (GAD-Ab)

Exclusion Criteria2

  • Secondary diabetes
  • Active malignancy or history of malignant tumor within the past 5 years

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Interventions

OTHERNo Interventions

No Interventions


Locations(1)

Tianjin medical university general hospital

Tianjin, China

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NCT07492004


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