Ultrasound Assessment of Femoral Vein and Inferior Vena Cava Collapsibility to Predict Spinal Anesthesia-Induced Hypotension
Evaluation of Inferior Vena Cava and Femoral Vein Collapsibility Indices for Predicting Post-Spinal Hypotension in Patients Undergoing Transurethral Prostate Resection: A Prospective Observational Study
Antalya Training and Research Hospital
110 participants
Jan 1, 2026
OBSERVATIONAL
Conditions
Summary
Spinal anesthesia is commonly used in transurethral prostate resection (TUR-P) surgeries; however, post-spinal hypotension remains a frequent and clinically significant complication, particularly in elderly patients. Early prediction of hypotension may allow timely interventions and improve patient safety. This prospective observational study aims to evaluate the predictive value of preoperative ultrasound-based inferior vena cava collapsibility index (IVC-CI) and femoral vein collapsibility index (FVCI) for post-spinal hypotension in patients undergoing elective TUR-P under spinal anesthesia. Before spinal anesthesia, IVC and femoral vein measurements will be obtained using ultrasonography. Hemodynamic parameters will be recorded before and after spinal anesthesia, and the occurrence of hypotension will be assessed according to predefined criteria. The study seeks to compare the diagnostic performance of IVC-CI and FVCI in predicting post-spinal hypotension and to identify potential clinical predictors associated with hypotension in this patient population.
Eligibility
Inclusion Criteria5
- Adult patients aged 18-75 years
- American Society of Anesthesiologists (ASA) physical status I-III
- Scheduled for elective transurethral resection of the prostate (TUR-P)
- Planned spinal anesthesia
- Ability to provide written informed consent
Exclusion Criteria13
- Refusal to participate in the study
- Body mass index (BMI) \>30 kg/m²
- Use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers
- Emergency surgery
- Baseline systolic arterial blood pressure \<90 mmHg or mean arterial pressure \<70 mmHg
- Major peripheral vascular disease or severe cardiovascular disease
- Unstable angina or left ventricular ejection fraction \<40%
- Chronic respiratory disease
- Increased intra-abdominal pressure
- Autonomic nervous system disorders
- Implanted pacemaker or implantable cardioverter-defibrillator
- Anticipated difficult airway
- Cognitive impairment or inability to cooperate
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Locations(1)
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NCT07497295