Effect of Dexamethasone on Post-spinal Hypotension
Effect of Dexamethasone on Post-spinal Hypotension in Geriatric Patients Undergoing Orthopaedic Surgery at Tertiary Care Hospital Karachi.
Shaheed Mohtarma Benazir Bhutto Institue of Trauma
170 participants
Feb 1, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries. The main question aim to answer is: Does intravenous dexamethasone in participants undergoing orthopedic procedures of lower limb under spinal anesthesia prevents post spinal hypotension? Researchers are comparing two groups of participants * Participants in (Dexamethasone Group) Group D are receiving intravenous dexamethasone 8mg preoperatively * Participants in (Placebo Group) Group P are receiving placebo preoperatively.
Eligibility
Inclusion Criteria1
- Patient undergoing orthopedic surgery in spinal anesthesia. ASA ≤ 2.
Exclusion Criteria1
- Patients with history of cardiac arrhythmias. Patients with history of acute coronary syndrome. Patient with history of polytrauma. Patients with contraindication to SA (e.g., coagulopathy, thrombocytopenia, allergy to local anesthetic agent) and those on steroids or serotonin related medications (e.g., selective serotonin reuptake inhibitor) will be excluded.
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Interventions
Intravenous dexamethasone 8mg given to participants before spinal anesthesia
Intravenous placebo given to the participants before spinal anesthesia
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06819436