RecruitingPhase 4NCT07499804

Effect of Tadalafil on Endometrial Thickness and Frozen Embryo Transfer Outcomes


Sponsor

Beni-Suef University

Enrollment

100 participants

Start Date

Oct 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

investigate the effect of different vasodilators as Tadalafil in women with unexplained infertility using IVF


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 43 Years

Inclusion Criteria1

  • has good quality day five frozen embryos.

Exclusion Criteria2

  • hypotension (blood pressure less than 90/50) and
  • history of stroke or myocardial infarction

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Interventions

DRUGTadalafil 5mg

phosphodiesterase type 5 (PDE-5) inhibitor

DRUGestradiol valerate 2 mg

estradiol valerate 2 mg. in form of (Cycloprogynova® Bayer Shering Pharma) white pills starting dose is one pill T.I.D may be increased to two pills T.I.D according to endometrial thickness in day 9 measured by vaginal ultrasound.


Locations(1)

Beni-suef university Hospital

Banī Suwayf, Beni Suweif Governorate, Egypt

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NCT07499804


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