RecruitingPhase 3NCT07505004

Double-blind, Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures

A Double-blind, Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures

Sponsor

Praxis Precision Medicines

Enrollment

300 participants

Start Date

Jan 29, 2026

Study Type

INTERVENTIONAL

Conditions

Focal Epilepsy

Summary

A multicenter, double-blind, randomized, placebo-controlled clinical trial to evaluate the efficacy and safety of vormatrigine in adults with focal seizures (POWER2)

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called 20 mg/day vormatrogine for 12 weeks, a drug called 30 mg/day vormatrogine for 12 weeks, and others for people with focal epilepsy. The study is currently recruiting participants at 7 locations. People eligible for this study include aged 18 Years to 85 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG40 mg/day vormatrogine for 12 weeks

Once daily oral

DRUG30 mg/day vormatrogine for 12 weeks

Once daily oral

DRUG20 mg/day vormatrogine for 12 weeks

Once daily oral

DRUGPlacebo

Once daily oral

Locations(7)

Praxis Research Site

Miami, Florida, United States

Praxis Research Site

Miami Lakes, Florida, United States

Praxis Research Site

Naples, Florida, United States

Praxis Research Site

Marlboro, New Jersey, United States

Praxis Research Site

Niagara Falls, New York, United States

Praxis Research Site

Raleigh, North Carolina, United States

Praxis Research Site

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT07505004

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