Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy
Analgesic Efficacy of Low-Volume Versus Standard-Volume 0.25% Bupivacaine for Ultrasound-Guided External Oblique and Rectus Abdominis Plane Block in Laparoscopic Cholecystectomy, A Randomized Non-Inferiority Trial
Fayoum University Hospital
96 participants
Apr 12, 2026
INTERVENTIONAL
Conditions
Summary
The original EXORA block used high local anesthetic volume (50 mL total), raising concerns about local anesthetic systemic toxicity (LAST). In such a bilaterally administered regional technique, evaluating the efficacy of a reduced-volume approach is warranted to maximize patient safety.
Eligibility
Plain Language Summary
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Interventions
15 mL of bupivacaine 0.25% administered bilaterally by ultrasound guided EXORA block
25 mL of bupivacaine 0.25% administered bilaterally by ultrasound guided EXORA block
Locations(1)
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NCT07507799