RecruitingNot ApplicableNCT07517484

Light and Anesthesia

Effects and Mechanisms of Ambient Light Intensity on the Depth of General Anesthesia

Sponsor

Peking University People's Hospital

Enrollment

66 participants

Start Date

Oct 3, 2025

Study Type

INTERVENTIONAL

Conditions

Anesthesia Sedation Light

Summary

The objective of this clinical trial is to investigate the effect of light exposure on sedation depth during general anesthesia.The primary research questions this study aims to address include: Does light condition affect the dosage of anesthetic medications during anesthesia? By what mechanism does light exposure exert an influence on anesthesia? Participants will be randomly allocated to either the light-shielded group or the non-light-shielded group.Patients in the light-shielded group will wear an eye shield during anesthesia. The following data will be recorded for all patients: Induction drug dosage Induction time Intraoperative anesthetic dosage Emergence time

Eligibility

Min Age: 18 YearsMax Age: 64 Years

Inclusion Criteria4

a. Age between 18 and 65 years, regardless of gender;
b. ASA physical status I-II;
c. 18.5 ≤ BMI ≤ 28;
d. Signed written informed consent.

Exclusion Criteria7

a. Blindness or history of photosensitivity disorders;
b. Patients requiring medication for sleep, or with a history of sleep disorders;
c. Presence of neurological diseases;
d. Pregnancy;
e. Severe hepatic or renal dysfunction;
f. History of anesthetic drug abuse or alcohol abuse;
g. History of adverse anesthesia events (difficult airway, allergy to anesthetic agents).

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Interventions

DEVICEeye mask

Patients in the light-shielded group will wear an opaque eye mask 30 minutes prior to induction of general anesthesia and continue to do so until the cessation of sedative medications for anesthesia.