Sedation Clinical Trials

24 recruiting

Sedation Trials at a Glance

61 actively recruiting trials for sedation are listed on ClinicalTrialsFinder across 6 cities in 25 countries. The largest study group is Not Applicable with 19 trials, with the heaviest enrollment activity in Boston, Ann Arbor, and Beijing. Lead sponsors running sedation studies include Ankara City Hospital Bilkent, Massachusetts General Hospital, and Tanta University.

Browse sedation trials by phase

Treatments under study

About Sedation Clinical Trials

Looking for clinical trials for Sedation? There are currently 24 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sedation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sedation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 61 trials

Recruiting
Not Applicable

Dexmedetomidine and Propofol for Sedation in Cataract Surgery.

Nausea and VomitingDexmedetomidineSedation+7 more
Saint-Joseph University1,000 enrolled1 locationNCT07556133
Recruiting
Not Applicable

Effect of Remimazolam With Protocolized Sedation on Critical Ill, Mechanical Ventilated Patients Compared With Midazolam

Sedation and Analgesia
Zhujiang Hospital440 enrolled1 locationNCT05160987
Recruiting
Phase 2

Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaCritical Care, Intensive Care
Beth Israel Deaconess Medical Center300 enrolled1 locationNCT07224620
Recruiting
Not Applicable

Sedation in ICU Patients With Mechanical Ventilation

Mechanical VentilationSedation
Zhongda Hospital366 enrolled1 locationNCT06538883
Recruiting

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

SurgeryAnesthesiaSedation+6 more
Massachusetts General Hospital1,200,000 enrolled1 locationNCT07022951
Recruiting
Not Applicable

Light and Anesthesia

AnesthesiaSedationLight
Peking University People's Hospital66 enrolled1 locationNCT07517484
Recruiting

Investigation of Sedation Depth Via BIS Monitoring in ICU After Cardiac Surgery

Sedation After Cardiac Surgery
Medical University of Graz50 enrolled2 locationsNCT07350109
Recruiting

PRedictors Of Maladaptive Behaviors in Children Undergoing Procedural SEDation

Procedural Sedation and Analgesia
London Health Sciences Centre Research Institute2,145 enrolled2 locationsNCT07495826
Recruiting
Not Applicable

EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and Sedatives

Sedation and AnalgesiaCholangiopancreatography, Endoscopic Retrograde
Chi Kwan Fung20 enrolled1 locationNCT07211828
Recruiting
Not Applicable

TEAS for Sedation During ERCP: A Multicenter Trial

Procedural PainEndoscopic Retrograde CholangiopancreatographyConscious Sedation Adverse Event+1 more
Beijing 302 Hospital130 enrolled1 locationNCT07440342
Recruiting

Comparison of Nasal Continuous Positive Airway Pressure (CPAP) Mask and Nasal Airway in Molar Tooth Extraction Under Deep Sedation

Deep SedationNon-invasive Ventilation SupportNasal Airway+2 more
Gözde Nur Erkan60 enrolled2 locationsNCT06436638
Recruiting
Not Applicable

Study of the Efficacy of Moderate Sedation With Intra-NAsal Dexmedetomidine Monitored by EEG MOnitoring

Pediatric ALLProcedural Sedation and Analgesia
Centre Hospitalier Régional Metz-Thionville50 enrolled1 locationNCT06867289
Recruiting
Not Applicable

Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.

Pediatric SedationClonidine SedationKetamine Sedation
Cairo University84 enrolled1 locationNCT07461376
Recruiting
Phase 1Phase 2

Prospective IR-led Sedation Feasibility

AnesthesiaSedation and AnalgesiaInterventional Radiology
CAMC Health System40 enrolled1 locationNCT07443254
Recruiting
Phase 3

Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration

AnesthesiaSedationEndoscopy
Massachusetts General Hospital100 enrolled1 locationNCT07269808
Recruiting
Phase 4

A Comparison of Remimazolam Besylate and Propofol Sedation in Patients Undergoing Colonoscopic Polypectomy

Colonic PolypSedation Complication
Clinical Hospital Centre Zagreb90 enrolled1 locationNCT07456111
Recruiting
Phase 4

Effect of IV Lidocaine on Duodenal Peristalsis and Sedation in ERCP

SedationERCPDuodenal Spasm
Ankara City Hospital Bilkent120 enrolled1 locationNCT07333859
Recruiting
Phase 4

Inhaled Sedation in Critically Ill Patients

SedationAirway Extubation
Instituto de Investigación Hospital Universitario La Paz620 enrolled22 locationsNCT07000526
Recruiting

Impact of Cannabis Use During Third Molar Surgery

Cannabis UseMarijuana UsageSedation and Analgesia+1 more
University of Michigan242 enrolled1 locationNCT07423195
Recruiting
Phase 3

Optimizing Pain Treatment in Children On Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaAnalgesics, Opioid+1 more
Weill Medical College of Cornell University644 enrolled15 locationsNCT06994442