Sedation Clinical Trials

71 recruitingLast updated: June 18, 2026

There are 71 actively recruiting sedation clinical trials across 33 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1. Top locations include Boston, Massachusetts, United States, Ann Arbor, Michigan, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Sedation Trials at a Glance

71 actively recruiting trials for sedation are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 22 trials, with the heaviest enrollment activity in Boston, Ann Arbor, and Beijing. Lead sponsors running sedation studies include Ankara City Hospital Bilkent, Guy's and St Thomas' NHS Foundation Trust, and Massachusetts General Hospital.

Browse sedation trials by phase

Treatments under study

About Sedation Clinical Trials

Looking for clinical trials for Sedation? There are currently 25 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sedation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sedation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 71 trials

Recruiting
Phase 2Phase 3

Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome

Mechanical Ventilation ComplicationAcute Respiratory Distress SyndromeSedation Complication
Guy's and St Thomas' NHS Foundation Trust20 enrolled1 locationNCT06014138
Recruiting
Not Applicable

Light and Anesthesia

AnesthesiaSedationLight
Peking University People's Hospital66 enrolled1 locationNCT07517484
Recruiting
Phase 4

Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

DexmedetomidinePediatric SedationRecovery Time+3 more
Boston Children's Hospital105 enrolled1 locationNCT07369128
Recruiting
Phase 3

Effect of Remimazolam Sedation on Outcomes of Mechanically Ventilated Patients in the ICU

SedationMechanically Ventilated ICU PatientsRemimazolam Besylate
Southeast University, China80 enrolled1 locationNCT07596589
Recruiting

Tolerability of Remimazolam Versus Midazolam in EUS

Sedation During GI Endoscopy
Azienda Socio Sanitaria Territoriale di Lecco126 enrolled1 locationNCT07600073
Recruiting
Phase 4

Inhaled Sedation in Critically Ill Patients

SedationAirway Extubation
Instituto de Investigación Hospital Universitario La Paz620 enrolled22 locationsNCT07000526
Recruiting
Not Applicable

BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation

Atrial FibrillationDeep SedationElectric Countershock
Istanbul University - Cerrahpasa60 enrolled1 locationNCT07569016
Recruiting
Not Applicable

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)

TemperatureBlood PressureCardiac Arrest (CA)+9 more
Helsinki University Central Hospital3,500 enrolled52 locationsNCT07579390
Recruiting

Modeling and Closed-loop Control of Depth of Anaesthesia

The Focus is to Develop a Closed-loop Control System for Anaesthesia in Vitroretinal Surgery, Surgery Due to Expansive Processes in Head, and Long-term Sedation
University of Ljubljana50 enrolled1 locationNCT03569839
Recruiting

Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol

Intensive Care MedicineOpioid analgesiaExtracorporeal Membrane Oxygenation (ECMO)+5 more
Guy's and St Thomas' NHS Foundation Trust120 enrolled1 locationNCT07032987
Recruiting
Not Applicable

Neurosteer Bedside Monitoring System

DeliriumSedationAgitation
Icahn School of Medicine at Mount Sinai100 enrolled1 locationNCT06718764
Recruiting
Not Applicable

Dexmedetomidine and Propofol for Sedation in Cataract Surgery.

Nausea and VomitingDexmedetomidineSedation+7 more
Saint-Joseph University1,000 enrolled1 locationNCT07556133
Recruiting
Phase 2

Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaCritical Care, Intensive Care
Beth Israel Deaconess Medical Center300 enrolled1 locationNCT07224620
Recruiting
Not Applicable

Effect of Remimazolam With Protocolized Sedation on Critical Ill, Mechanical Ventilated Patients Compared With Midazolam

Sedation and Analgesia
Zhujiang Hospital440 enrolled1 locationNCT05160987
Recruiting
Not Applicable

Sedation in ICU Patients With Mechanical Ventilation

Mechanical VentilationSedation
Zhongda Hospital366 enrolled1 locationNCT06538883
Recruiting

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

SurgeryAnesthesiaSedation+6 more
Massachusetts General Hospital1,200,000 enrolled1 locationNCT07022951
Recruiting

Investigation of Sedation Depth Via BIS Monitoring in ICU After Cardiac Surgery

Sedation After Cardiac Surgery
Medical University of Graz50 enrolled2 locationsNCT07350109
Recruiting

PRedictors Of Maladaptive Behaviors in Children Undergoing Procedural SEDation

Procedural Sedation and Analgesia
London Health Sciences Centre Research Institute2,145 enrolled2 locationsNCT07495826
Recruiting
Not Applicable

EEG and Pain Monitor Data Under Anesthesia to Study Pharmacodynamic Effects of Opioids and Sedatives

Sedation and AnalgesiaAnesthesia GeneralCholangiopancreatography, Endoscopic Retrograde
Chi Kwan Fung20 enrolled1 locationNCT07211828
Recruiting
Not Applicable

TEAS for Sedation During ERCP: A Multicenter Trial

Procedural PainEndoscopic Retrograde CholangiopancreatographyConscious Sedation Adverse Event+1 more
Beijing 302 Hospital130 enrolled1 locationNCT07440342