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RecruitingNCT07521111

Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients

Study on the Predictive Value of Gastrointestinal Blood Flow for Enteral Nutrition Intolerance in Critically Ill Patients

Sponsor

Ruijin Hospital

Enrollment

500 participants

Start Date

Jan 25, 2026

Study Type

OBSERVATIONAL

Conditions

Critical IllnessEnteral Nutrition FeedingMachine LearningPrediction ModelsEnteral Nutrition Intolerance

Summary

This study aims to explore the correlation between gastrointestinal blood flow and the incidence of enteral nutrition intolerance (ENI) and its symptoms in critically ill patients, construct and compare predictive models including blood flow parameters, and evaluate their incremental predictive value.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Age > 18 years old.
  • Expected duration of enteral nutrition support > 7 days.
  • Patients or their legal representatives sign the informed consent form.

Exclusion Criteria5

  • History of major gastrointestinal surgery such as subtotal gastrectomy and gastrointestinal anastomosis.
  • Contraindications to abdominal point-of-care ultrasound (POCUS) examination (e.g., recent large-area abdominal burns, dressings blocking movement, open abdomen).
  • Presence of severe gastrointestinal diseases such as gastroparesis, intestinal obstruction, digestive tract perforation, and gastrointestinal bleeding upon admission.
  • Presence of severe peripheral vascular disease or valvular heart disease.
  • Pregnant or lactating women.

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Locations(1)

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, China

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NCT07521111

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