Critical Illness Clinical Trials

13 recruiting

Frequently Asked Questions

Common questions about Critical Illness clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Not Applicable

Behavioral Health Collaborative Care Model in an ICU Recovery Clinic

AnxietyDepression - Major Depressive DisorderCritical Illness+6 more
Medical University of South Carolina150 enrolled1 locationNCT07372586
Recruiting
Not Applicable

Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

AnxietyDepression - Major Depressive DisorderPTSD+4 more
Medical University of South Carolina150 enrolled1 locationNCT07390786
Recruiting

IL-6 and Hemogram-Derived Inflammatory Indices for Mortality Prediction in Postoperative ICU Patients

Postoperative ComplicationsInflammationCritical Illness+1 more
Ezgi Günaydın42 enrolled1 locationNCT07460141
Recruiting
Not Applicable

Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.

Heart FailureCritical IllnessLVAD
Karlsburg Hospital30 enrolled1 locationNCT07034599
Recruiting
Not Applicable

Music Listening: A Mechanistic Trial

Critical Illness
University of Pittsburgh171 enrolled1 locationNCT05541029
Recruiting

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

Respiratory FailureCardiac FailureAcute Respiratory Distress Syndrome+4 more
Barts & The London NHS Trust100 enrolled1 locationNCT03753412
Recruiting
Phase 4

Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients

Critical Illness
Scarborough General Hospital3,253 enrolled5 locationsNCT07173855
Recruiting

Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation

Cirrhosis, LiverCritical Illness
University Hospital, Lille226 enrolled2 locationsNCT04530760
Recruiting
Phase 2Phase 3

Azithromycin for Critical Asthma - Pediatrics

Critical IllnessPediatric Asthma
Johns Hopkins All Children's Hospital100 enrolled1 locationNCT06223828
Recruiting
Phase 3

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

Post Traumatic Stress DisorderDeliriumCritical Illness+2 more
Vanderbilt University Medical Center372 enrolled1 locationNCT04801589
Recruiting
Phase 4

Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients

Critical IllnessNew Onset Atrial Fibrillation
Dr. Stephanie Sibley200 enrolled4 locationsNCT05829317
Recruiting
Not Applicable

A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

Cognitive ImpairmentDementiaCognitive Decline+5 more
University of Washington100 enrolled1 locationNCT06411561
Recruiting
Not Applicable

Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

AnxietyRespiratory FailureCritical Illness
Johns Hopkins University60 enrolled1 locationNCT06341972
Recruiting
Not Applicable

Ultrasound Airway Assessment of Critically Ill Preeclamptic; Comparison Between Two Technique

Critical IllnessPre-EclampsiaDifficult; Intubation, Postpartum, During Puerperium
Ain Shams University50 enrolled1 locationNCT06651879
Recruiting
Not Applicable

Post Intensive Care Unit Atrial Fibrillation

Atrial FibrillationCritical Illness
Centre Hospitalier Universitaire de Besancon150 enrolled1 locationNCT05860894