RecruitingNot ApplicableNCT07525973

The Effect of Eye Exercises in Parkinson's Disease

The Effect of Eye Exercises on Physical Function, Balance, and Fall Risk in Patients With Parkinson's Disease: A Randomized Controlled Trial


Sponsor

Pardis Specialized Wellness Institute

Enrollment

34 participants

Start Date

May 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Parkinson's disease is commonly associated with impaired gait, postural instability, reduced physical function, and increased concern about falling, all of which contribute substantially to disability and reduced quality of life. Exercise-based rehabilitation is increasingly recommended as a core non-pharmacological strategy for improving mobility and balance in people with Parkinson's disease. In parallel, recent clinical and neurorehabilitation research suggests that eye-movement and gaze-stabilization training may influence postural control, visuomotor integration, and movement performance in neurological disorders, including Parkinson's disease. This randomized controlled trial will evaluate whether a supervised in-center eye-exercise program can improve physical function, balance, and fall-related concern in patients with Parkinson's disease.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria1

  • Aged 18 years and older Clinically diagnosed idiopathic Parkinson's disease Hoehn and Yahr stage 1-3 Stable antiparkinsonian medication regimen Able to stand unaided and walk with or without an assistive device Able to provide written informed consent Able to attend supervised in-center exercise sessions Able to follow simple exercise instructions

Exclusion Criteria1

  • Severe cognitive impairment Unstable cardiovascular, orthopedic, or neurologic conditions that interfere with safe participation Active infection or acute medical illness Hemodynamic instability Severe visual impairment or other sensory impairment that prevents participation Recent myocardial infarction or stroke Unstable or changing antiparkinsonian medication regimen Any other condition that, in the judgment of the study physician, makes participation unsafe

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Interventions

BEHAVIORALSupervised In-Center Eye Exercises

The participants in the study group will perform the eye-exercise program in a supervised rehabilitation/clinic setting. The exercises will initially be performed in a seated position, with selected tasks progressed to standing positions as tolerated and considered safe by the supervising therapist. The exercises will be administered face-to-face by trained study personnel. The program will include progressive visual fixation, smooth pursuit, saccadic eye movements, convergence/divergence, gaze stabilization, and combined eye-head coordination tasks, with gradual progression in speed and complexity according to participant tolerance and safety.


Locations(1)

Pardis specialized wellness institute

Isfahan, Iran

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NCT07525973


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