Effect of Different Meal Types Given Before Exercise on Plasma Amino Acid Levels and Metabolic Control Parameters in Classical Phenylketonuria Patients Undergoing Aerobic and Resistance Exercises
Hacettepe University
10 participants
Oct 1, 2025
INTERVENTIONAL
Conditions
Summary
This study will be the first in the literature to evaluate the relationship between aerobic and resistance exercises, plasma amino acid levels, metabolic control of patients, and the metabolic response to exercise with different types of meals in patients with Phenylketonuria (PKU). In patients with phenylketonuria, the aim is to determine which pre-exercise dietary recommendations are more physiologically appropriate and ideal for achieving good metabolic control. In the literature, there are very few studies examining the effects of exercise on plasma amino acid levels and metabolic parameters in PKU patients.
Eligibility
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Interventions
Participants performed 30 minutes of moderate-intensity aerobic exercise on a treadmill at 80% of maximum heart rate with a 3% incline.
Participants performed a resistance exercise session including 3 sets of 10 repetitions of crunch, push-up, forward lunge, and squat exercises.
Participants consumed 200 ml of water prior to the exercise session.
Participants consumed carbohydrates at a dose of 1 g/kg/hour prior to the exercise session.
Participants consumed protein equivalent to 0.4 g/kg/hour (amino acids) prior to the exercise session.
Locations(1)
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NCT07526909