RecruitingPhase 1NCT07241234

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-181 in Subjects With Phenylketonuria

A Phase 1b, Open-label, Multicenter, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of AG-181 in Subjects With Phenylketonuria


Sponsor

Agios Pharmaceuticals, Inc.

Enrollment

20 participants

Start Date

Apr 17, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The primary purpose of this study is to assess the safety and tolerability of AG-181 in subjects with Phenylketonuria (PKU).


Eligibility

Min Age: 18 YearsMax Age: 69 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called AG-181 for people with phenylketonuria. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years to 69 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAG-181

AG-181 film-coated tablets


Locations(4)

Indiana University

Indianapolis, Indiana, United States

UPMC Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, United States

University of Texas Southwestern Medical Center (UTSW)

Dallas, Texas, United States

Centrum Wsparcia Badań Klinicznych Pomorskiego Uniwersytetu Medycznego w Szczecinie

Szczecin, West Pomeranian Voivodeship, Poland

View Full Details on ClinicalTrials.gov

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NCT07241234


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