RecruitingEarly Phase 1NCT07531264

EMG-guided Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction

Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation

Sponsor

University of Houston

Enrollment

48 participants

Start Date

Oct 10, 2023

Study Type

INTERVENTIONAL

Conditions

Stroke

Summary

The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients to individually activate groups of synergistic muscles through human-machine interaction. Ultimately, the development will lead to better clinical motor recovery, better quality of life, and lowered healthcare costs associated with the impairment.

Eligibility

Min Age: 21 YearsMax Age: 80 Years

Inclusion Criteria4

Ischemic or hemorrhagic stroke
Aged between 21 and 80 years
Not receiving botulinum toxin on the impaired arm within 3 months
MAS ≤ 3 around elbow and shoulder

Exclusion Criteria5

have an orthopedic disorder involving upper limbs;
cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol (Montreal Cognitive Assessment (MoCA) score =< 26);
a history of another neurologic disease;
anesthesia of joint position sense in upper limbs;
are pregnant or have a chance that they might be (self-reported);

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERNeuromuscular coordination-guided rehabilitative training

During training exercise, post-stroke participants will be asked to match the targets on the screen. The experimental group will match them by activating a specific set of muscle. During assessment trials, a physical therapist or occupational therapist will rate the functional level of arm impairment using FMA and ARAT.

OTHERForce strengthening-guided rehabilitative training

During training exercise, post-stroke participants will be asked to match the targets on the screen. The active comparator group will match them by generating isometric force in a desired target direction. During assessment trials, a physical therapist or occupational therapist will rate the functional level of arm impairment using FMA and ARAT.