RecruitingPhase 1NCT07536061

A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease

A Randomized, Double-Blind, Placebo-Controlled, Dose Escalation Study to Evaluate the Effect of SRP-1005 in Subjects With Huntington's Disease (INSIGHTT)


Sponsor

Sarepta Therapeutics, Inc.

Enrollment

32 participants

Start Date

May 12, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This is a first-in-human, multi-center trial studying the effects of SRP-1005 in participants with Huntington's disease (HD).


Eligibility

Min Age: 21 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called SRP-1005 for people with huntington’s disease. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 21 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSRP-1005

Subcutaneous injection

DRUGPlacebo

Subcutaneous injection


Locations(4)

Westmead Hospital

Westmead, New South Wales, Australia

New Zealand Brain Research Institute

Christchurch, New Zealand

Siloah AG

Gümligen, Canton of Bern, Switzerland

University Hospital of Wales

Cardiff, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT07536061


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