RecruitingPhase 2NCT07543120

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

A Multicenter Open-label Extension Study to Evaluate Long-term Safety and Efficacy of QCZ484 in Hypertensive Patients.

Sponsor

Novartis Pharmaceuticals

Enrollment

323 participants

Start Date

May 7, 2026

Study Type

INTERVENTIONAL

Conditions

Hypertension (HTN)

Summary

The purpose of this extension study is to collect additional safety and efficacy on QCZ484 for hypertensive patients who successfully completed the parent study, CQCZ484A12201 or additional QCZ484 studies as specified in the respective parent study protocols.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called QCZ484 for people with hypertension (htn). The study is currently recruiting participants at 13 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGQCZ484

QCZ484 subcutaneous injection, Q6M.

Locations(25)

NICRs Research Center

Garden Grove, California, United States

Downtown L A Research Center Inc

Los Angeles, California, United States

Clinical Research of Brandon LLC

Brandon, Florida, United States

Entrust Clinical Research

Miami, Florida, United States

Inpatient Research Clinical LLC

Miami Lakes, Florida, United States

American Research Centers of FL

Pembroke Pines, Florida, United States

Cen Exel FCR

Tampa, Florida, United States

Cardiology Partners Clinical Research Institute

Wellington, Florida, United States

Javara Research

Fayetteville, Georgia, United States

Eagle Clinical Research

Chicago, Illinois, United States

Alliance for Multispecialty Research

Wichita, Kansas, United States

Anderson Medical Research

Ft. Washington, Maryland, United States

Oakland Medical Research Center

Troy, Michigan, United States

Jefferson City Medical Group

Jefferson City, Missouri, United States

CenExel HRI

Berlin, New Jersey, United States

Monroe Biomedical Research

Monroe, North Carolina, United States

Conrad Clinical Research

Edmond, Oklahoma, United States

Clinical Neuroscience Solutions Inc

Memphis, Tennessee, United States

Sun Research Institute

San Antonio, Texas, United States

Novartis Investigative Site

Suita, Osaka, Japan

Novartis Investigative Site

Chuo Ku, Tokyo, Japan

Novartis Investigative Site

Chuo-ku, Tokyo, Japan

Novartis Investigative Site

Shinjuku Ku, Tokyo, Japan

Novartis Investigative Site

Singapore, Singapore

Novartis Investigative Site

Singapore, Singapore

View Full Details on ClinicalTrials.gov

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NCT07543120

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