RecruitingNot ApplicableNCT07213479

Feasibility and Acceptability of Isometric Exercise and Lifestyle Change for the Management of Hypertension

Feasibility and Acceptability of Remote Home-Based Isometric Exercise and Lifestyle Change for the Management of Hypertension


Sponsor

Northumbria University

Enrollment

70 participants

Start Date

Feb 2, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

High blood pressure (hypertension) is a leading risk factor for cardiovascular diseases and may contribute to poor health and premature death. The purpose of this research is to learn if a home-based isometric exercise programme combined with lifestyle change advice is a practical and acceptable method for people diagnosed with hypertension to manage their condition. Isometric exercise involves a muscle contraction without movement of the limbs and previous research has shown this may be effective for reducing blood pressure. Therefore, this study will explore the experiences, thoughts, attitudes, and barriers to participation. It will also examine the effect the isometric exercise has on blood pressure. Participants will undertake an isometric exercise programme using a wall squat position, 3 times per week, for 12 weeks. The exercise sessions will be completed at home with remote online supervision by an exercise professional. Lifestyle change advice will given in line with current guidelines to promote healthy behaviours to reduce high blood pressure. After 12 weeks, participants will be encouraged to continue with the wall squat exercise for a further 12-weeks unsupervised. Throughout the study, participants' blood pressure and daily activity will be recorded using a smartwatch device. Upon completion of the intervention period, participants will be interviewed to gather their views and opinions on the isometric exercise programme. Changes in blood pressure will be evaluated at 12 and 24 weeks. By exploring whether an isometric exercise programme is a feasible and acceptable method for hypertensive people to manage their condition and how this influences blood pressure, this research may aid in the development of a strategy to manage hypertension.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a specific type of exercise called isometric exercise (where you tense muscles without movement, like squeezing a handgrip) combined with lifestyle changes can lower blood pressure in people with high blood pressure who are already on medication. **You may be eligible if...** - You have been diagnosed with high blood pressure (hypertension) - You have been on blood pressure medication at the same dose for at least 4 months - Your blood pressure is below 180/110 mmHg - You have not been doing any regular structured exercise program for at least the past 3 months **You may NOT be eligible if...** - Your BMI is above 35 - You have heart disease beyond high blood pressure - You have a joint, muscle, or nerve condition that would prevent you from doing these exercises - Your high blood pressure is caused by another medical condition (secondary hypertension) - You have difficulty following instructions or completing the study protocol Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALIsometric Exercise and Lifestyle Change Advice

The intervention consists of two distinct phases: • Intensive Phase (12 weeks) - a structured, high-support period involving three weekly supervised isometric exercise sessions and lifestyle change advice. The supervised exercise programme will consist of 4 × 2-minute bouts of wall squat exercise, with 2-minute rest periods between bouts. Participant squat height position will be based on individual calculations determined at baseline. Target rate of perceived exertion (RPE) for each bout will be: * Bout 1: RPE 4 (target range: 3.5-4.5) * Bout 2: RPE 5.5 (target range: 5-6) * Bout 3: RPE 7 (target range: 6.5-7.5) * Bout 4: RPE 8.5 (target range: 8-9) If the RPE falls outside the target zone for a given bout, participants will adjust their squat height accordingly. Lifestyle change advice will be given in booklet form in accordance with current NICE guidelines for hypertension. • Maintenance Phase (12-24 weeks) - focus on sustaining exercise and lifestyle behaviour changes

BEHAVIORALLifestyle Change Advice

Lifestyle change advice given as per current standard care for hypertension


Locations(1)

Northumbria University

Newcastle upon Tyne, United Kingdom

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NCT07213479


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