RecruitingPhase 1NCT07543861

A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

Sponsor

University of Michigan

Enrollment

5 participants

Start Date

Apr 1, 2026

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases. Phase 1 will be an open-label study and Phase 2 will be an in-lab randomized controlled trial pilot study. This is phase 1 of the study.

Eligibility

Min Age: 50 Years

Inclusion Criteria1

Diagnosis of Parkinson's Disease

Exclusion Criteria10

Inability to stand or walk without an assistive device
History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects
Any other history of medical or psychiatric comorbidity, precluding safe participation in the project.
History of symptomatic cardiovascular or pulmonary disease
History of active rheumatic arthritis
History of stroke or other neurologic conditions with significant residual sensorimotor deficits
History of disabling chronic pain syndrome requiring narcotic analgesics
Evidence of dementia (Mini Mental State Exam (or Montreal Cognitive Assessment test) <24 and significant impairment in activities of daily living)
Venous ulcerative stasis or severe varicosities.
Pregnancy as determined by urine pregnancy test prior to DXA procedure in women of childbearing potential.

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Interventions

DEVICEDynamic Standing Desk

Participants will stand at the desk for 4 hours per session. During each session, the desk will move to prompt the participant to take small steps. Participants will take breaks as needed. Each participant will complete up to 12 sessions in the span of 6 weeks.