RecruitingNCT07549048

Caregiver Burden in Caregivers of Patients With Multiple Sclerosis

The Relationship Between Mood, Insomnia Severity, and Caregiver Burden in Caregivers of Patients With Multiple Sclerosis

Sponsor

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Enrollment

50 participants

Start Date

Apr 20, 2026

Study Type

OBSERVATIONAL

Conditions

Multiple Sclerosis

Summary

Individuals aged 18-80 years who have been clinically diagnosed with multiple sclerosis and their caregivers will be included in the study. Demographic data of the patients, including age, height, weight, and comorbidities, will be recorded. Disease-specific characteristics such as disease duration, presence of incontinence, ambulation status, and presence and severity of pain will be assessed. Functional status of the patients will be evaluated using the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Impact Scale (MSIS). Symptoms related to depression and anxiety in patients will be assessed using the Hospital Anxiety and Depression Scale (HADS). Subsequently, caregivers of the patients will be evaluated. The severity of insomnia will be assessed using the Insomnia Severity Index (ISI). Symptoms related to anxiety and depression will be evaluated using the Hospital Anxiety and Depression Scale (HADS). Caregiver burden will be assessed using the Zarit Caregiver Burden Scale.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria6

Age 18-80 years
Clinically diagnosed with multiple sclerosis by a neurologist
Being followed in the physical therapy and rehabilitation clinics during the study period
Having a primary or regular caregiver (family member)
Both patient and caregiver able to read and understand Turkish and complete questionnaires
Willing to participate and provide written informed consent

Exclusion Criteria7

Severe cognitive impairment or communication problems preventing questionnaire completion
Acute relapse or hospitalization due to exacerbation within the last month
Severe comorbid neurological, psychiatric, or systemic disease affecting assessments
Caregiver <18 years old or not providing regular care
Paid professional caregiver
Caregiver with severe psychiatric, neurological, or primary sleep disorder
Refusal to participate