RecruitingNCT07557433

Relationship Between Induction Burst Suppression and Bispectral Index

The Relationship Between Burst Suppression Observed During Anesthesia Induction and the Bispectral Index Value During the Maintenance Phase of Anesthesia


Sponsor

Amasya University

Enrollment

200 participants

Start Date

Jul 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to understand whether certain brain activity patterns that can appear at the beginning of anesthesia are related to how deep anesthesia remains during the operation. The main question of the study is: Do patients who show a pattern called burst suppression during the start of anesthesia experience deeper anesthesia during surgery? Patients who are scheduled for elective surgery under total intravenous anesthesia (TIVA) may take part in this study. During the operation, brain activity will be monitored using a sensor placed on the forehead (Bispectral Index, BIS monitor), which is already commonly used during anesthesia. Information such as BIS values and the doses of anesthesia medications given during the operation will be recorded. Participation in this study will not change the type of anesthesia or the routine care that patients receive during surgery. The study only involves recording and analyzing information collected during standard anesthesia monitoring.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria4

  • Age between 18 and 75 years
  • American Society of Anesthesiologists (ASA) physical status I-III
  • Scheduled for elective surgery
  • Surgery planned to be performed under total intravenous anesthesia (TIVA)

Exclusion Criteria4

  • Presence of neurological disease
  • Chronic use of sedative medications or antiepileptic drugs
  • Severe hepatic or renal dysfunction
  • Intraoperative administration of ketamine or dexmedetomidine

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Locations(2)

Amasya University Sabuncuoglu Serefeddin Training and Research Hospital

Amasya, Amasya, Turkey (Türkiye)

Izmir Katip Celebi University Ataturk Training and Research Hospital

Izmir, İzmir, Turkey (Türkiye)

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NCT07557433


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