RecruitingNot ApplicableNCT07558928

Effect of Hyperoxygenated Environment on Maximal Muscle Strength

Effect of Hyperoxygenated Environment on Maximal Muscle Strength in the Mid-thigh Pull Test - a Blinded, Randomized, Sham-Controlled Crossover Study

Sponsor

Assaf-Harofeh Medical Center

Enrollment

48 participants

Start Date

Jan 1, 2024

Study Type

INTERVENTIONAL

Conditions

Healthy Lifestyle

Summary

comparing the effect of hyperoxygenated environment on maximal muscle strength in the Mid-thigh Pull Task

Eligibility

Min Age: 18 YearsMax Age: 45 Years

Inclusion Criteria4

Healthy
Ages 18-45
Participants are physically active and have a recent resistance-training experience of at least six months, ≥ 3 times a week
Participant willing and able to read, understand and sign an informed consent

Exclusion Criteria11

Inability to attend scheduled clinic visits or comply with the study protocol
Active malignancy
Active smokers
Previous treatment of hyperbaric chamber for any reason prior to study enrollment.
Chest pathology incompatible with pressure changes
Major orthopedic injury at the past 3 months
Inner ear disease
Lung pathology
Claustrophobia
Previous neurologic conditions (e.g., epilepsy, brain tumors or s/p neurosurgery etc.)
Comorbidities and medications that rule out the subject

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Interventions

DEVICEHyperbaric Oxygen Therapy - HBOT

The HYPEROXYGENATED ENVIRONMENT protocol will include a single exposure to hyperoxic environment. The session will last 60 minutes, of 100% oxygen inhalation by mask at 2 ATA

DEVICESham

The Sham protocol will include a single session of breathing 21% oxygen by mask while in the same multi-place chamber. SHAM pressure will go up to 1.2 ATA during the first five minutes of the session (to simulate the pressure sensation in the ears), and then decrease during the next 5 minutes to 1.03 ATA for 55 minutes