RecruitingNot ApplicableNCT07559656

Oxytocin's Effects on Real Time-fMRI Neurofeedback Training of Anterior Insula Activity

Effects of Intransal Oxytocin on Real-time fMRI Neurofeedback Training of Anterior Insula Activity Using an Interoceptive Strategy


Sponsor

University of Electronic Science and Technology of China

Enrollment

80 participants

Start Date

Apr 26, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The primary aim of this study is to investigate whether intranasal oxytocin can modulate the real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback training effects by facilitating the use of an interoceptive strategy.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 30 Years

Inclusion Criteria1

  • Healthy subjects without any past or present psychiatric or neurological disorders.

Exclusion Criteria2

  • History of brain injury medical or mental illness.
  • Contraindication to MRI scanning (e.g., metal implants, claustrophobia or other --conditions that make them inappropriate for MRI scanning).

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Interventions

DRUGIntranasal oxytocin

Each subject will be assigned to intranasally administered 24-IU of oxytocin.

DRUGIntranasal placebo

Each subject will be assigned to intranasally administered 24-IU of placebo.


Locations(1)

University of Electronic Science and Technology of China

Chengdu, Sichuan, China

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NCT07559656


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