RecruitingNot ApplicableNCT07560267

Efficacy of Ultrasound-Guided Erector Spinae Block for Postoperative Pain Management in Nephrectomy

Efficacy of Ultrasound-Guided Erector Spinae Plane Block in Postoperative Pain Management in Nephrectomy: A Randomized Controlled Trial

Sponsor

Bangladesh Medical University

Enrollment

66 participants

Start Date

Sep 1, 2025

Study Type

INTERVENTIONAL

Conditions

Postoperative Pain Nephrectomy Erector Spinae Plane Block

Summary

This clinical trial aims to evaluate the effectiveness of the ultrasound-guided erector spinae plane (ESP) block in managing postoperative pain for patients undergoing open nephrectomy (kidney removal surgery). The study will compare this new technique to traditional pain management methods, such as opioid medications, to assess whether the ESP block reduces pain and the need for opioids after surgery. Patients will be randomly assigned to one of two groups: Group C will receive conventional pain relief methods, including opioids. Group E will receive the ultrasound-guided ESP block in addition to general anesthesia. The main goals are to determine: How much pain relief each method provides, measured using a visual analog scale (VAS). The total amount of opioids required during the first 24 hours post-surgery. Additional measurements will include monitoring vital signs like heart rate, blood pressure, and oxygen levels. This study will help find safer and more effective ways to manage pain after nephrectomy, reducing the reliance on opioids and improving patient recovery

Eligibility

Min Age: 18 YearsMax Age: 64 Years

Inclusion Criteria3

Adult patients aged 18 to 64 years
Scheduled for open nephrectomy (radical or partial) under general anesthesia
ASA physical status I-II (American Society of Anesthesiologists classification)

Exclusion Criteria6

Allergy to local anesthetics.
Local infection or inflammation at the site of the Block placement.
Presence of anatomical deformities in the spine
Coagulopathy or any bleeding disorder.
Pregnancy or breastfeeding women.
History of severe chronic pain syndrome

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Interventions

PROCEDUREUltrasound-Guided Erector Spinae Plane (ESP) Block

The Ultrasound-Guided Erector Spinae Plane (ESP) Block is a regional anesthesia technique used to provide postoperative pain relief. In this study, the intervention involves the administration of a local anesthetic (0.25% bupivacaine) into the fascial plane between the erector spinae muscle and the transverse process of the vertebra using ultrasound guidance. The procedure is performed immediately before the induction of general anesthesia in patients undergoing open nephrectomy. The goal of the ESP block is to reduce postoperative pain, minimize opioid consumption, and improve recovery outcomes while maintaining hemodynamic stability. This intervention is compared to conventional pain management methods, which primarily rely on systemic opioids and other standard analgesics.