RecruitingPhase 1NCT07567781

A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.

A Phase 1 Study to Evaluate the Effect of Multiple Doses of ABBV-722 on the Pharmacokinetics of Cocktail Probe Substrates of CYP3A and Select Transporters in Healthy Adult Subjects


Sponsor

AbbVie

Enrollment

12 participants

Start Date

Apr 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to assess the effect of repeated doses of ABBV-722 on the single dose pharmacokinetics (PK) of Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called ABBV-722, a drug called Digoxin, and others for people with healthy volunteers. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGABBV-722

Oral Tablet

DRUGMidazolam

Oral Solution

DRUGMetformin

Oral Tablet

DRUGDigoxin

Oral Tablet

DRUGPitavastatin

Oral Tablet

DRUGSitagliptin

Oral Tablet


Locations(1)

Acpru /Id# 282184

Grayslake, Illinois, United States

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NCT07567781


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