Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries
Effect of Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries Under General Anaesthesia; a Randomised Controlled Double Blinded Study
Ain Shams University
72 participants
May 1, 2026
INTERVENTIONAL
Conditions
Summary
This study will evaluate the effect of adding dexmedetomidine to bupivacaine compared to ketamine in the caudal block on perioperative analgesia in patients undergoing lumbosacral surgeries under general anesthesia.
Eligibility
Inclusion Criteria4
- Age 21-60 years.
- Sex: Both sexes.
- American Society of Anesthesiologists (ASA) Physical Status Class-I and II.
- Scheduled for lumbosacral surgery under General Anesthesia.
Exclusion Criteria5
- Declining to give written informed consent or patients with significant cognitive dysfunction that hinders informed consent.
- History of allergy to the medications used in the study.
- Contraindications to regional anesthesia (including coagulopathy and local infection).
- History of recent analgesic intake or abuse.
- Pregnancy or lactating mothers.
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Interventions
The patients will receive 20ml plain bupivacaine (0.125%) in the caudal block
The patients will receive 20ml plain bupivacaine (0.125%) + 2μg/kg dexmedetomidine in the caudal block
The patients will receive 20ml plain bupivacaine (0.125%) + 1mg/kg ketamine in the caudal block
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07573969