Perioperative Analgesia Modes in Minimally Invasive Esophagectomy

This study is comparing different methods of pain control after minimally invasive surgery to remove the esophagus (esophagectomy) — a major operation for esophageal cancer. Researchers want to find out which approach provides the best pain relief with the fewest side effects. **You may be eligible if...** - You are between 18 and 75 years old - You are scheduled for minimally invasive esophagectomy (laparoscopic, thoracoscopic, or robotic) - You have provided informed consent **You may NOT be eligible if...** - You have had cholecystitis (gallbladder inflammation) or kidney stones in the past 3 months - You have had a stroke, heart attack, or peripheral artery disease - You have lung disease, severe heart disease, or already have a chest drain - You drink heavily (more than defined safe limits) Talk to your doctor to see if this trial is right for you.