RecruitingNot ApplicableNCT07582913

Manual Versus Autoflow Ventilation During Anesthesia Inductıon in Geriatric Patients

Effects of Manual Versus Autoflow Ventilation During Anesthesia Induction on Cerebral and Peripheral Oxygenation in Geriatric Patients

Sponsor

Ankara City Hospital Bilkent

Enrollment

106 participants

Start Date

May 13, 2026

Study Type

INTERVENTIONAL

Conditions

Ventilation Cerebral Oxygenation Geriatrics Near-Infrared Spectroscopy Peripheral Oxygenation

Summary

The objective of this study is to compare the effects of manual ventilation and AutoFlow ventilation, administered during the induction of general anesthesia, on cerebral (s-rSO₂) and peripheral (somatic) oxygenation (p-rSO₂) in geriatric patients.

Eligibility

Min Age: 65 Years

Inclusion Criteria4

Patients aged 65 years and older.
Patients scheduled to undergo elective surgery requiring endotracheal intubation under general anesthesia.
Patients with an American Society of Anesthesiologists (ASA) physical status of I, II, or III.
Volunteer patients who are willing to participate and provide written informed consent.

Exclusion Criteria5

Patients with severe heart failure or severe pulmonary disease.
Patients with a presence or history of brain tumors or cerebrovascular accidents (CVA/stroke).
Patients with impaired cooperation or cognitive dysfunction (e.g., dementia, delirium, Alzheimer's disease).
Patients with a known history or preoperative prediction of a difficult airway.
Patients with a known allergy to the monitoring sensor materials.

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Interventions

PROCEDUREManual Mask Ventilation

Patients will receive manual mask ventilation with 100% oxygen using a reservoir bag. This procedure will be performed by an experienced anesthesiologist or anesthesia resident for 2 minutes following the administration of induction agents, allowing for adequate muscle relaxation prior to endotracheal intubation.

PROCEDUREAutoFlow Mechanical Mask Ventilation

Patients will receive mask ventilation delivered mechanically by the anesthesia workstation. The device will provide 100% oxygen for 2 minutes following the administration of induction agents. The ventilator settings will be standardized to an AutoFlow mode with a tidal volume (VT) of 6 mL/kg (based on ideal body weight), a respiratory rate of 12 breaths/minute, a peak pressure limit of 30 cmH₂O, and a Positive End-Expiratory Pressure (PEEP) of 5 cmH₂O