Effect of Magnesium-, Vitamin C- and Grape Seed Extract-Enriched Date Bars on Perceived Stress and Salivary Cortisol Levels in Young Women
A Randomized Controlled Trial Evaluating the Effects of Functional Date Bars Enriched With Magnesium, Vitamin C, and Grape Seed Extract on Perceived Stress and Salivary Cortisol in Healthy Young Women
K.G. Razumovsky Moscow State University of Technologies and Management
34 participants
May 22, 2026
INTERVENTIONAL
Conditions
Summary
This randomized controlled trial aims to evaluate the effect of a 4-week daily consumption of a functional date bar enriched with magnesium, vitamin C, and grape seed extract on perceived stress and salivary cortisol levels in healthy young women. Participants will be randomly assigned to either an intervention group receiving the enriched bar or a control group receiving a placebo bar identical in appearance and taste. Primary outcomes include changes in salivary cortisol levels and perceived stress (PSS-14).
Eligibility
Inclusion Criteria3
- BMI 17.0-29.9 kg/m²
- Living in Moscow region
- Provided informed consent
Exclusion Criteria6
- Diagnosed psychiatric disorders
- Use of glucocorticoids or hormonal medications
- Use of dietary supplements containing magnesium, vitamin C, or polyphenols
- Chronic endocrine disorders
- Baseline salivary cortisol <1.5 ng/mL
- Allergy to bar components
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Interventions
Daily consumption of a functional date-based bar enriched with magnesium (240 mg), vitamin C (300 mg), and grape seed extract (100 mg) for 4 weeks.
Daily consumption of a date-based bar in which all active ingredients are replaced with maltodextrin, for 4 weeks.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07585422