RecruitingNot ApplicableNCT07588230

Serratus Posterior Superior Intercostal Plane Block in Minimally Invasive Cardiac Surgery

Preoperative Serratus Posterior Superior Intercostal Plane Block for Analgesia and Opioid Sparing in Patients Undergoing Minimally Invasive Cardiac Valve Surgery Via Mini-Thoracotomy: A Randomized, Double-Blind, Placebo-Controlled Trial

Sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Enrollment

90 participants

Start Date

May 16, 2026

Study Type

INTERVENTIONAL

Conditions

Postoperative Pain Heart Valve Disease

Summary

This randomized, double-blind, placebo-controlled study aims to evaluate the effect of the serratus posterior superior intercostal plane (SPSIP) block on postoperative pain and opioid consumption in patients undergoing minimally invasive cardiac valve surgery via mini-thoracotomy.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria5

Adult patients aged 18-75 years
ASA physical status I-III
Scheduled for elective minimally invasive cardiac valve surgery via mini-thoracotomy
Able to understand and use the Numeric Rating Scale (NRS)
Provided written informed consent

Exclusion Criteria10

Age >75 years
Known allergy or hypersensitivity to local anesthetics (e.g., bupivacaine)
Coagulopathy or ongoing anticoagulant therapy that cannot be discontinued
Infection at the planned block site
Chronic opioid use or chronic pain conditions
Severe pulmonary disease affecting respiratory assessment
Neurological or psychiatric disorders interfering with pain assessment
Emergency surgery
Pregnancy or breastfeeding
Refusal to participate

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Interventions

PROCEDURESerratus Posterior Superior Intercostal Plane Block With Bupivacaine

Participants in this group will receive an ultrasound-guided serratus posterior superior intercostal plane (SPSIP) block prior to surgery using 30 mL of 0.25% bupivacaine, in addition to standard general anesthesia and multimodal analgesia.

PROCEDURESerratus Posterior Superior Intercostal Plane Block With Saline

Participants in this group will receive an ultrasound-guided placebo block using 30 mL of normal saline under identical conditions, in addition to standard general anesthesia and multimodal analgesia.