RecruitingPhase 1NCT07593092

Phase 1, Safety and Tolerability Study of XmAb541 and XmAb808 in Advanced Solid Tumors

A Phase 1 Trial, Evaluating the Safety and Tolerability of XmAb541 in Combination With XmAb808 in Advanced Solid Tumors


Sponsor

Xencor, Inc.

Enrollment

90 participants

Start Date

Jun 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The primary purpose of this study is to determine whether the combination of the investigational drug XmAb541 in combination with the investigational drug XmAb808 is safe and well tolerated, and to determine an optimal and safe dose(s) for further study. The study will also evaluate the effect of XmAb541 in combination with XmAb808 on participants' tumor outcomes.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called XmAb541 and a biological treatment called XmAb808 for people with ovarian cancer. The study is currently recruiting participants at 4 locations. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALXmAb541

Monoclonal Bispecific Antibody

BIOLOGICALXmAb808

Monoclonal Bispecific Antibody


Locations(4)

Xencor Investigative Site

Lake Success, New York, United States

Xencor Investigative Site

New York, New York, United States

Xencor Investigative Site

The Bronx, New York, United States

Xencor Investigative Site

Fort Worth, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT07593092


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