Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder
Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder Receiving Buprenorphine
Prisma Health-Upstate
70 participants
Nov 12, 2025
OBSERVATIONAL
Conditions
Summary
This study examines the effects of e-cigarette (EC) flavors among adults with opioid use disorder (OUD) receiving buprenorphine treatment who currently use e-cigarettes. Participants will smell and rate 11 EC flavors based on appeal, sensory characteristics, and likelihood of future use. Researchers will examine how different flavor profiles influence the appeal and reinforcing effects of ECs in this population. The goal is to identify EC flavors that may enhance the acceptability of ECs as a potential harm-reduction strategy among adults with OUD receiving buprenorphine treatment.
Eligibility
Inclusion Criteria5
- Adults aged 21 years or older.
- Current e-cigarette users who report e-cigarette use on ≥20 of the past 30 days.
- Former daily cigarette smokers who currently smoke on ≤19 days per month and no more than 5 cigarettes per day.
- Diagnosed with opioid use disorder (OUD).
- Currently receiving buprenorphine treatment for OUD.
Exclusion Criteria1
- \-
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Interventions
Sweet-cooling EC flavor
Sweet non-cooling flavor
Tobacco flavor EC
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07594717