RecruitingNot ApplicableNCT07597980

Lifestyle Intervention to Improve Muscle Function in Older Adults


Sponsor

Pennington Biomedical Research Center

Enrollment

80 participants

Start Date

Jul 20, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized controlled two-arm trial is to determine the effect of a diet and exercise intervention for 12 weeks on body composition, muscle function, and energy balance in 80 adults aged 50 years and over with obesity and insulin resistance. The main questions the trial aims to answer are: Will 12 weeks of a structured nutrition plan + exercise reduce fat mass, improve muscle function, and increase energy deficit compared to the usual diet + exercise. The hypothesis is that 12 weeks of a structured nutrition plan + exercise will reduce fat mass, improve muscle function, and produce greater energy deficit than the usual diet + exercise. Participants will be provided with all meals for 12 weeks and will exercise at the Center under supervision three times each week. Pre and post-intervention, body composition, physical function, and energy deficit will be measured.


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Structured nutrition plan, a behavioral approach called Supervised Exercise, and others for people with body composition, energy balance, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALStructured nutrition plan

Participants will receive a structured nutrition plan.

BEHAVIORALTypical or usual diet

Participants will receive a diet representing the usual diet in this population.

BEHAVIORALSupervised Exercise

Participants will complete aerobic and resistance training under supervision three times per week.


Locations(1)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, United States

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NCT07597980


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