RecruitingPhase 1NCT07600749

Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001)

A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of MK-4884 in Participants With Advanced/Metastatic Solid Tumors


Sponsor

Merck Sharp & Dohme LLC

Enrollment

120 participants

Start Date

Jun 18, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Researchers are looking for new ways to treat certain types of advanced and/or metastatic solid tumors. The main goal of this study is to learn about the safety of different doses of MK-4884 and if participants tolerate them.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called MK-4884 for people with malignant neoplasm. The study is currently recruiting participants at 4 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMK-4884

Oral Administration


Locations(5)

NEXT Oncology ( Site 0151)

San Antonio, Texas, United States

Rambam Health Care Campus ( Site 0051)

Haifa, Israel

Rabin Medical Center ( Site 0053)

Petah Tikva, Israel

National Cancer Center Hospital ( Site 0201)

Chūō, Tokyo, Japan

Ospedale Regionale Bellinzona e Valli ( Site 0104)

Bellinzona, Canton Ticino, Switzerland

View Full Details on ClinicalTrials.gov

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NCT07600749


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