RecruitingPhase 3NCT07602582

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

An Annual Dosing Study of Donanemab in Participants Who Completed Donanemab Study AACM

Sponsor

Eli Lilly and Company

Enrollment

550 participants

Start Date

May 22, 2026

Study Type

INTERVENTIONAL

Conditions

Dementia Alzheimer Disease Plaque, Amyloid

Summary

The main purpose of this study is to determine if participants who previously took donanemab get clinical benefit when they receive annual doses. For each participant, the study will last up to 2.5 years and will include 6 visits.

Eligibility

Min Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Donanemab and a drug called Placebo for people with alzheimer disease, dementia, and other related conditions. The study is currently recruiting participants at 58 locations. People eligible for this study include aged 55 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDonanemab

Administered IV

DRUGPlacebo

Administered IV

Locations(59)

Banner Alzheimer's Institute

Phoenix, Arizona, United States

Care Access - Huntington Beach

Huntington Beach, California, United States

Irvine Clinical Research

Irvine, California, United States

Healthy Brain Clinic

Long Beach, California, United States

Artemis Institute for Clinical Research

Riverside, California, United States

Clinical Trials Research

Sacramento, California, United States

Artemis Institute for Clinical Research

San Diego, California, United States

Syrentis Clinical Research

Santa Ana, California, United States

Providence Medical Foundation

Santa Rosa, California, United States

Infectious Disease Doctors Medical Group, APC

Walnut Creek, California, United States

VIN - Aventura

Aventura, Florida, United States

Bradenton Research Center, Inc.

Bradenton, Florida, United States

Finlay Medical Research

Greenacres City, Florida, United States

Jacksonville Center for Clinical Research

Jacksonville, Florida, United States

K2 Medical Research ORLANDO

Maitland, Florida, United States

Merritt Island Medical Research, LLC

Merritt Island, Florida, United States

Finlay Medical Research

Miami, Florida, United States

VIN-Andrew Lerman

Miami, Florida, United States

Indago Research & Health Center, Inc

Miami Lakes, Florida, United States

Adult Medicine of Lake County, Inc.

Mt. Dora, Florida, United States

Suncoast Clinical Research, Inc.

New Port Richey, Florida, United States

Charter Research - Orlando

Orlando, Florida, United States

Headlands Research Orlando

Orlando, Florida, United States

Emerald Coast Neurology - Airport Boulevard

Pensacola, Florida, United States

Progressive Medical Research

Port Orange, Florida, United States

Care Access - Tampa

Tampa, Florida, United States

K2 Medical Research - Tampa

Tampa, Florida, United States

Charter Research - The Villages

The Villages, Florida, United States

Conquest Research

Winter Park, Florida, United States

Center for Advanced Research & Education

Gainesville, Georgia, United States

North Georgia Clinical Research

Woodstock, Georgia, United States

Northwest Clinical Trials

Boise, Idaho, United States

Great Lakes Clinical Trials - Andersonville

Chicago, Illinois, United States

Care Access - South Indianapolis

Indianapolis, Indiana, United States

Josephson Wallack Munshower Neurology, PC

Indianapolis, Indiana, United States

Covenant Medical Center

Waterloo, Iowa, United States

Care Access - Lake Charles (Bayou Pines)

Lake Charles, Louisiana, United States

Boston Center for Memory

Newton, Massachusetts, United States

MedVadis Research Corporation

Waltham, Massachusetts, United States

Revival Research Institute, LLC

Southfield, Michigan, United States

Citizens Memorial Hospital District

Bolivar, Missouri, United States

Vector Clinical Trials

Las Vegas, Nevada, United States

The Cognitive and Research Center of New Jersey

Springfield, New Jersey, United States

Monroe Biomedical Research

Monroe, North Carolina, United States

NDx Clinical Research, Inc.

Dayton, Ohio, United States

Care Access - Lima

Lima, Ohio, United States

Senior Adults Specialty Research

Austin, Texas, United States

Gadolin Research

Beaumont, Texas, United States

The University of Texas Health Science Center at Houston

Houston, Texas, United States

Consano Clinical Research, LLC

Shavano Park, Texas, United States

Northwest Clinical Research Center

Bellevue, Washington, United States

Universal Research Group

Tacoma, Washington, United States

Tokyo-Eki Center-building Clinic

Chūōku, Japan

P-One Clinic

Hachiōji, Japan

National Center for Geriatrics and Gerontology

Ōbu, Japan

Samoncho Clinic

Shinjuku, Japan

Yotsuya Internal Medicine Clinic

Shinjyuku, Japan

Tokyo Metropolitan Institute for Geriatrics and Gerontology

tabashi City, Japan

SCB Research Center

Bayamón, Puerto Rico

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07602582

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