RecruitingNCT07603128

Multicenter Validation of a Risk Prediction Model for MDRGNB Infection

Prospective Validation of a Risk Prediction Model for MDRGNB Infection: A Multicenter Real-World Prospective Study


Sponsor

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Enrollment

1,000 participants

Start Date

May 22, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective multicenter validation study aimed to evaluate the predictive performance of a previously developed model for MDRGNB infection in ICU patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age ≥18 years;
  • ICU stay ≥48 hours;
  • At least one clinical microbiological specimen collected and submitted for testing within 48 hours of ICU admission, with the first submission time designated as the index time;
  • Core predictive variables of the model extractable from electronic medical records or laboratory information systems.

Exclusion Criteria3

  • For patients with multiple ICU admissions, only the first ICU stay was retained;
  • Missing or indeterminate primary outcome;
  • Missing key predictive variables that could not be handled according to prespecified rules.

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Locations(11)

Nanjing Drum Tower Hospital

Nanjing, Jiangsu, China

Ankang People's Hospital

Ankang, China

Sinopharm Tongmei General Hospital

Datong, China

First Affiliated Hospital of Gannan Medical University

Ganzhou, China

Zhejiang Hospital

Hangzhou, China

Zhejiang Provincial People's Hospital

Hangzhou, China

Huaian First People's Hospital

Huaian, China

Guangxi Provincial Tumor Hospital

Nanning, China

Shanghai Ruijin Hospital

Shanghai, China

Shaanxi Provincial People's Hospital

Xi'an, China

Zhanjiang Central People's Hospital

Zhanjiang, China

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NCT07603128


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