RecruitingNot ApplicableNCT07609628

Effect of Silicon Oil on Retinal Electrical Functions Using Multifocal Electroretinogram

Effect of Silicon Oil on Retinal Electrical Functions in Patients With Rhegmatogenous Retinal Detatchment Using Multifocal Electroretinogram .

Sponsor

Minia University

Enrollment

50 participants

Start Date

Feb 1, 2026

Study Type

INTERVENTIONAL

Conditions

rhegmatogenous retinal detachment

Summary

Retinal detachment is one of the leading causes for permanent vision loss.Incidence of Rheugmatogenous Retinal Detachment (RRD) about 10.5 people per 100,000 population pars plana vitrectomy is the most popular and effective surgical options. Tamponade agents as silicone oils are used to restore intraocular volume and apply surface tension to the detached retinal surface Silicone oil (SO) is a liquid containing polymerized siloxane with organic side chains. It has a high thermal stability, is hydrophobic, and chemically inert. The use of silicone oils as intraocular tamponades dates from 1962.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria1

\- Patients with primary rhegmatogenous retinal detachment

Exclusion Criteria7

Patients with history of previous intraocular surgery.
Patients with combined traction-rhegmatogenous retinal detachment
Patients with ocular disease as glaucoma ,degenerative myopia,age related macular degeneration
Patients with poor fixation.
Uncooperative patients.
Patients with retinopathy.
emulsified SO or complicated SO removal were excluded from this study

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Interventions

DEVICEMulti focal electroretinogram

to evaluat the effect of silicon oil on retinal function in the eyes that underwent Pars Plana Vitrectomy with Silicon oil tamponade for Rheugmatogenous Retinal Detachment. mfERG responses were recorded before and after Silicon oil removal .