RecruitingPhase 3NCT07613307

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting

A Phase 3b, Multicenter, Multi-Country, Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of Orforglipron in Adult Participants With Type 2 Diabetes Who Observe Ramadan Fasting (ACHIEVE-RAM)

Sponsor

Eli Lilly and Company

Enrollment

130 participants

Start Date

Jul 15, 2026

Study Type

INTERVENTIONAL

Conditions

Diabetes Mellitus, Type 2 Endocrine System Diseases Behavior Metabolic Disorders Glucose Metabolism Disorders Nutritional and Metabolic Diseases Feeding Behavior Fasting Diabetes Melletus Glucagon-Like Peptide-1 Receptor Glucagon-Like Peptide Receptors Receptors, G-Protein-Coupled Receptors, Cell Surface Membrane Proteins Proteins Receptors, Peptide

Summary

The purpose of this study is to test the efficacy and safety of orforglipron in participants with T2D (type 2 diabetes) who participate in fasting during Ramadan. For each participant, the study will last up to 48 weeks with a minimum of 7 in clinic visits and 4 virtual visits.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Orforglipron for people with behavior, diabetes melletus, and other related conditions. The study is currently recruiting participants at 40 locations. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOrforglipron

Administered orally

Locations(40)

Sarojini Naidu Medical College

Agra, India

Osmania General Hospital

Hyderabad, India

Brij Medical Centre Pvt. Ltd.

Kanpur, India

Apollo Multispeciality Hospitals limited

Kolkata, India

KGN Diabetes and Endocrinology Centre

Mumbai, India

Mysore Medical College and Research Institute

Mysore, India

Supe Heart & Diabetes Hospital & Research Centre

Nashik, India

Diabetes Clinic

Nellore, India

Visakha Institute of Medical Sciences

Visakhapatna, India

King Abdulaziz University for Health Sciences Ministry of National Guard Health Affairs

Al-Ahsa, Saudi Arabia

King Fahad Specialist Hospital

Dammam, Saudi Arabia

Imam Abdulrahman Bin Faisal University

Dammam, Saudi Arabia

National Guard Health Affairs: King Abdulaziz Medical City

Jeddah, Saudi Arabia

King Abdulaziz University Hospital

Jeddah, Saudi Arabia

King Fahad Armed Forces Hospital Jeddah

Jeddah, Saudi Arabia

Dr. Soliman Fakeeh Hospital

Jeddah, Saudi Arabia

King Saud University Medical City

Riyadh, Saudi Arabia

Dr. Soliman Fakeeh Hospital

Riyadh, Saudi Arabia

Osepdale Fatebenefratelli e Oftalmico

Riyadh, Saudi Arabia

JOSHA Research

Bloemfontein, South Africa

TREAD Research

Cape Town, South Africa

TASK Central

Cape Town, South Africa

Tiervlei Trial Centre

Cape Town, South Africa

Synopsis Research

Cape Town, South Africa

Synergy Biomed Research Institute (SBRI)

East London, South Africa

Aliwal Shoal Medical Centre

eMkhomazi, South Africa

Fola Health

Johannesburg, South Africa

Trident Clinical

Kimberley, South Africa

Ubuntu Clinical Research Krugersdorp

Krugersdorp, South Africa

Drs H & V Makan Centre for Diabetes

Lenasia, South Africa

Be Part Research (PTY) LTD

Paarl, South Africa

Emmed Research

Pretoria, South Africa

Dr JM Engelbrecht Trial Site

Somerset West, South Africa

Burjeel Medical City

Abu Dhabi, United Arab Emirates

NMC Royal hospital

Abu Dhabi, United Arab Emirates

Sheikh Khalifa Medical City

Abu Dhabi, United Arab Emirates

NMC Abu Dhabi

Abu Dhabi, United Arab Emirates

Tawam Hospital

Al Ain City, United Arab Emirates

Emirates Hospital Dubai

Dubai, United Arab Emirates

Dubai Hospital

Dubai, United Arab Emirates

View Full Details on ClinicalTrials.gov

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NCT07613307

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