RecruitingNot ApplicableNCT07626593

The Extraordinary Endurance of the Human Species


Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Enrollment

40 participants

Start Date

Feb 3, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

We hypothesize, based on field and scientific data, that setting a very ambitious goal such as completing a mountain ultra-marathon could motivate sedentary and inactive individuals not only to begin training but also to follow a progressive yet extremely ambitious program that has not yet been studied comprehensively. Indeed, the effects of intense and prolonged endurance training (18 months) on the health and performance of completely sedentary individuals have never been investigated exhaustively.


Eligibility

Min Age: 25 YearsMax Age: 50 Years

Inclusion Criteria4

  • Affiliation to social security.
  • Informed consent signed.
  • Male or female, aged 25-50.
  • Sedentary (>6h/day sitting) and inactive (no regular training), assessed by GPAQ questionnaire.

Exclusion Criteria8

  • Chronic joint or cardiac diseases.
  • Neurological disorders.
  • Legal protection status.
  • Moderate to severe depression (BDI-13 > 7) or use of antidepressants/anxiolytics.
  • Use of banned substances.
  • Excessive alcohol or caffeine consumption.
  • Pregnancy.
  • Inability to understand or consent.

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Interventions

BEHAVIORALIntensive training

participants will follow individualized coaching: starting at 5-6 hours per week and progressing to 7-10 hours (rarely 15 hours) per week before mountain ultra marathon


Locations(1)

CHU de Saint-Etienne

Saint-Etienne, France

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NCT07626593


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