RecruitingPhase 2NCT07632872

Desloratadine as Adjunct Therapy for Rheumatoid Arthritis

Effect of Desloratadine as Add-On Therapy in Rheumatoid Arthritis


Sponsor

Horus University

Enrollment

60 participants

Start Date

May 23, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Rheumatoid arthritis is a chronic inflammatory disease that causes joint pain, swelling, and reduced physical function. Although standard disease-modifying antirheumatic drugs are effective for many patients, some individuals continue to have active disease. The purpose of this study is to evaluate the effectiveness and safety of adding desloratadine to standard therapy in patients with active rheumatoid arthritis. Participants will receive either desloratadine or placebo in addition to their usual treatment. The study will assess changes in disease activity and inflammatory markers over a follow-up period of approximately 12 weeks. The results of this study may help determine whether desloratadine could be a useful add-on treatment option for patients with rheumatoid arthritis.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Desloratadine 5 mg and a drug called Placebo for people with rheumatoid arthritis and rheumatoid arthritis (ra). The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDesloratadine 5 mg

Desloratadine administered orally as add on therapy to standard disease modifying antirheumatic drugs.

DRUGPlacebo

Matching placebo administered orally as add on therapy to standard disease modifying antirheumatic drugs.


Locations(1)

Faculty of medicine, Mansoura University

Al Mansurah, Egypt

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NCT07632872


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