RecruitingNot ApplicableNCT07636343

Eccentric Muscle Training in Cardiac Rehabilitation

Eccentric Muscle Training in Cardiac Rehabilitation: Randomized Controlled Trial to Evaluate Effectiveness and Feasibility in Heart Failure Patients With Reduced Ejection Fraction


Sponsor

University Hospital, Antwerp

Enrollment

3 participants

Start Date

Jan 20, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used. Researchers will compare a training program of eccentric overload training and eccentric cycling training with a traditional training program of strength and cardio training in people with heart failure with reduced ejection fraction. This study will be delivered in a cardiac rehabilitation setting.


Eligibility

Inclusion Criteria3

  • HFrEF patients with ejection fraction <40%
  • Exercise intolerance (<85% of predicted VO2 peak)
  • clinically stable for > 6 weeks, optimal medical treatment for > 6 weeks

Exclusion Criteria5

  • Contra indications for cardiac exercise rehabilitation as per consensus guidelines and recommendations
  • Musculoskeletal disorders that hamper (progression in) strength training
  • Non-stabilized acute coronary syndrome
  • Current acute heart failure (decompensation)
  • Patient having sustained a recent (<3 months) procedure that could act as a confounder to increase VO2peak (i.e., coronary artery bypass graft surgery, percutaneous coronary intervention, cardiac resynchronization therapy, valve surgery or reparation)

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Interventions

OTHEReccentric bike training

progressive following protocol, 10min

OTHEReccentric overload training

dynamic strength training + eccentric overload, progressive over time, 3sets\*10reps (15-20min)

OTHERaerobic treadmill training

aerobic training, progressive over time, 10 min

OTHERaerobic bike training

aerobic training, progressive following protocol, 10 min

OTHERtraditional dynamic strength training

dynamic strength training, progression over time, 15-20 min


Locations(1)

UHAntwerp

Edegem, Belgium

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