RecruitingEarly Phase 1NCT07638319

Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction

Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry


Sponsor

Egas Moniz - Cooperativa de Ensino Superior, CRL

Enrollment

30 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction. The main question it aims to answer is whether using β-TCP for alveolar ridge preservation has a positive effect on bone volume compared with natural healing. The main questions it aims to answer are: Does β-TCP improve ridge preservation compared with natural healing? Researchers will compare β-TCP grafted sockets to natural healing sockets to see if β-TCP better preserves ridge volume. Participants will: Have a tooth indicated for extraction. Be assigned to either β-TCP or natural healing. Undergo CBCT (Cone Beam Computed Tomography) and intra-oral scanning after extraction and after six months of healing to measure horizontal and vertical resorption and bone density.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • years or older
  • Acceptance of informed consent
  • Type 1 or 2 extraction sockets (Elian et al. 2007)

Exclusion Criteria7

  • Presence of active infection or severe inflammation in the intervention zone
  • Relevant medical history that contraindicates implant surgery
  • Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score >15%) and lack of motivation
  • Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%)
  • Uncontrolled and /or untreated periodontal disease
  • Heavy smokers (more than 10 cigarettes per day)
  • Immunosuppression

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Interventions

DEVICENeocement Inject P® (Beta-Tricalcium Phosphate)

After tooth extraction the socket will be grafted with Neocement Inject P® (Beta-Tricalcium Phosphate).


Locations(1)

Clinica Dentária Egas Moniz

Caparica, Monte Da Caparica, Portugal

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NCT07638319


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