RecruitingNot ApplicableNCT07641361

Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy

Hydration Intervention to Address Dehydration Associated With Use of GLP-1 Based Medications


Sponsor

State University of New York at Buffalo

Enrollment

30 participants

Start Date

Jun 15, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This is a 17 - week study consisting of a one - week run - in period and a 16 - week intervention. The 16 - week pilot interventions aims to increase hydration in those beginning GLP - 1 RA therapy. Investigators aim to increase hydration to potentially decrease side effect severity, amount of side effects, and drug discontinuation associated with GLP - 1 RA therapy. The investigators are piloting to assess feasibility and preliminary efficacy of the intervention through examining participant retention, participant feedback, researcher and participant adherence to protocols, impact on hydration biomarkers, and participant reported GLP - 1 RA side effects.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Control and a behavioral approach called Hydration Plus for people with dehydration, obesity type 2 diabetes mellitus, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALHydration Plus

The hydration plus intervention aims to increase hydration through employing the following behavior change strategies/techniques: coaching (consisting of goal setting, making a plan, and coping planning), positive feedback, and utilize a contingency management payment schedule wherein participant earned amount hinges on them meeting their goal.

BEHAVIORALControl

Participants randomly assigned to the control group will receive information on hydration and will receive prompts to drink.


Locations(1)

State University of New York at Buffalo, South Campus

Buffalo, New York, United States

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NCT07641361


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