Resting Energy Expenditure in Pediatric Patients With Inflammatory Bowel Disease (REE-MICI)
Measurement of Basal Metabolism in Patients With Crohn's Disease and Ulcerative Colitis and Correlation With Disease Activity.
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
50 participants
May 1, 2025
OBSERVATIONAL
Conditions
Summary
This multicenter prospective observational non-pharmacological study aims to evaluate resting energy expenditure (REE) in pediatric patients affected by inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. REE will be measured using indirect calorimetry and estimated using predictive equations. The study also aims to investigate the relationship between REE, disease activity, and dietary or pharmacological treatments. Clinical, laboratory, anthropometric, nutritional, and disease activity data will be collected during routine clinical follow-up at diagnosis, after induction therapy, and during follow-up visits.
Eligibility
Inclusion Criteria3
- Pediatric patients aged 6 to 17 years
- New diagnosis of inflammatory bowel disease, including Crohn disease or ulcerative colitis, according to ECCO/ESPGHAN criteria
- Written informed consent signed by parents or legal guardians
Exclusion Criteria3
- Intestinal surgery within 6 weeks before the first evaluation
- Parenteral or enteral nutrition within 6 weeks before the first evaluation
- Eating disorders or other chronic diseases associated with possible malabsorption
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Interventions
Resting energy expenditure (REE) assessment performed using indirect calorimetry in pediatric patients with inflammatory bowel disease during routine clinical follow-up. Measurements are obtained under resting conditions after fasting and are used to evaluate energy metabolism and its relationship with disease activity and treatments.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07670975