RecruitingNCT07677631

Emotional Allodynia Questionnaire (AEQ) in Fibromyalgia (PEARL)

Pain, Emotional Allodynia, and Relational Load (PEARL): A Multicenter Validation Study of the Emotional Allodynia Questionnaire in Fibromyalgia


Sponsor

University of Bari

Enrollment

423 participants

Start Date

Sep 10, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The Emotional Allodynia Questionnaire (AEQ) is an 11-item self-report instrument that measures disproportionate emotional reactivity to low-intensity interpersonal cues(perceived unresponsiveness, exclusion, loss of reciprocity), a pattern termed emotional allodynia. It was preliminarily validated in a single-center fibromyalgia sample. PEARL (validation phase) is a multicenter, prospective, observational psychometric validation study that (1) replicates the internal structure and convergent validity of the AEQ in an independent fibromyalgia sample, (2) tests its known-groups (discriminative) accuracy in separating fibromyalgia from non-fibromyalgia chronic pain of defined nociceptive or neuropathic origin, expressed as the area under the ROC curve (AUC), and (3) assesses test-retest reliability. There is no intervention.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with chronic pain, fibromyalgia, and other related conditions. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(5)

Pain Unit, Policlinico di Bari, University of Bari Aldo Moro (coordinating center)

Bari, Italy

Anesthesia and Pain Therapy Unit, IRCCS AOSP di Bologna, Policlinico S. Orsola-Malpighi

Bologna, Italy

Department of Medical Sciences and Public Health, University of Cagliari

Cagliari, Italy

Department of Women, Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli

Naples, Italy

Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona

Verona, Italy

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NCT07677631


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