RecruitingNot ApplicableNCT07685587

COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURY

Comparison of the Effects of Flexible and Navigable Suction With Conventional Ureteral Access Sheaths During Retrograde Intrarenal Surgery on Postoperative Acute Renal Injury With IL-18 and L-FABP Biomarkers: A Prospective Randomised Study


Sponsor

Namik Kemal University

Enrollment

108 participants

Start Date

May 4, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Kidney stone disease is a common condition, and retrograde intrarenal surgery (RIRS) is a minimally invasive procedure frequently used to remove kidney stones. During RIRS, pressure inside the kidney can increase, which may contribute to temporary kidney injury. New aspiration-enabled access sheath systems have been developed to better control this pressure by continuously removing irrigation fluid during surgery. This study will compare aspiration and conventional access sheath systems to determine whether improved pressure control reduces early kidney injury. Blood and urine biomarkers (IL-18 and L-FABP), which can detect kidney damage earlier than standard kidney function tests, will be measured before and after surgery. The results may help identify surgical techniques that better protect kidney function and improve the safety of kidney stone treatment for patients.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called conventional ureteral access sheath and a medical device called flexible and navigable ureteral access sheath for people with urolithiasis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEflexible and navigable ureteral access sheath

Patients of RIRS operated with flexible and navigable ureteral access sheath

DEVICEconventional ureteral access sheath

Patients of RIRS operated with conventional ureteral access sheath


Locations(1)

Tekirdag Namık Kemal University

Tekirdağ, Turkey (Türkiye)

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NCT07685587


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