Urolithiasis Clinical Trials

24 recruitingLast updated: May 21, 2026

There are 24 actively recruiting urolithiasis clinical trials across 12 countries. Studies span Not Applicable, Phase 1, Phase 2. Top locations include Birmingham, Alabama, United States, Dallas, Texas, United States, Shatin, Hong Kong. Updated daily from ClinicalTrials.gov.


Urolithiasis Trials at a Glance

24 actively recruiting trials for urolithiasis are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in Birmingham, Dallas, and Shatin. Lead sponsors running urolithiasis studies include University of Alabama at Birmingham, Northwestern University, and Chinese University of Hong Kong.

Browse urolithiasis trials by phase

About Urolithiasis Clinical Trials

Looking for clinical trials for Urolithiasis? There are currently 23 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Urolithiasis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Urolithiasis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 24 trials

Recruiting
Not Applicable

Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration Technology

Renal StonesKidney StonesUrolithiasis+1 more
Calyxo, Inc.150 enrolled3 locationsNCT07101809
Recruiting
Not Applicable

Comparing Efficiency and Stone-Free Rates Mini PCNL vs Flex URS

Kidney StonesNephrolithiasisUrolithiasis
Northwestern University80 enrolled1 locationNCT07072598
Recruiting
Not Applicable

Antibiotic Prophylaxis for Ureteroscopy With a Negative Pressure Suction Sheath

AntibioticsUrolithiasis
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine500 enrolled1 locationNCT07246967
Recruiting

Shear Wave Elastography for Predicting Extracorporeal Shock Wave Lithotripsy Outcomes in Pediatric Renal Stones

Pediatric Urolithiasis
Beni-Suef University108 enrolled1 locationNCT07506031
Recruiting
Not Applicable

PMCF Investigation of MODULITH® SLX-F2 With StorM-Track in Patients With Kidney Stones

Kidney StonesUrolithiasis
Storz Medical AG126 enrolled1 locationNCT07272720
Recruiting
Not Applicable

Evaluation of Quality of Life in Patients After Placement of a Modified Double J Ureteral Stent

Quality of LifeUrolithiasisUreteral Double-J Stent
St. Luke's Clinical Hospital, Russia40 enrolled1 locationNCT07275879
Recruiting
Not Applicable

Efficacy of Neorenal Forte for the Complete Elimination of Residual Fragments

Urolithiasis
Neopharm Bulgaria Ltd.120 enrolled9 locationsNCT06651294
Recruiting
Not Applicable

A Single-Center Clinical Study on the Efficacy and Safety of VISOR

Kidney StoneUrolithiasis, Calcium Oxalate
Second Affiliated Hospital, School of Medicine, Zhejiang University20 enrolled1 locationNCT07071948
Recruiting
Not Applicable

Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure

Kidney DiseasesNephrolithiasisUrolithiasis+3 more
Northwestern University126 enrolled1 locationNCT05100017
Recruiting
Not Applicable

The Use of AR / VR in Patients Presenting to the ED With Renal Colic

Renal ColicKidney Stones, Urolithiasis, Hypocitraturia
Community Medical Center, Toms River, NJ92 enrolled1 locationNCT07070401
Recruiting
Not Applicable

Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

HealthyHealthy VolunteerKidney Stones+6 more
University of Alabama at Birmingham80 enrolled2 locationsNCT06989320
Recruiting
Not Applicable

Comparing Different Diameter fURSs With Similar RESDs for the Treatment of Upper Urinary Tract Stones

Efficacy, SelfUreter InjuryUrolithiasis; Lower Urinary Tract
Ningbo No. 1 Hospital206 enrolled1 locationNCT06987760
Recruiting
Not Applicable

ILY Robotic System vs Manual Flexible Ureteroscopy for Kidney Stone Treatment

Kidney StonesUrolithiasis
Albert El Hajj152 enrolled1 locationNCT06996587
Recruiting
Not Applicable

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

HealthyNephrolithiasisKidney Stone+6 more
University of Alabama at Birmingham80 enrolled2 locationsNCT06331546
Recruiting
Not Applicable

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

NephrolithiasisKidney StoneUrolithiasis+5 more
University of Alabama at Birmingham40 enrolled2 locationsNCT06330246
Recruiting
Phase 1Phase 2

Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

Post Operative PainUrolithiasisStent Complication+1 more
University of Texas Southwestern Medical Center80 enrolled1 locationNCT06158620
Recruiting

Renal Stone Treatment Global Registry

Urolithiasis
Chinese University of Hong Kong3,000 enrolled3 locationsNCT05297331
Recruiting

The Effect of Preoperative Culture Timing on Postoperative Outcomes of Retrograde Intrarenal Surgery

urinary infectionsUrolithiasis
Namik Kemal University1,000 enrolled1 locationNCT06723327
Recruiting
Not Applicable

Comparison of Stent-Related Symptoms Between Anti-Reflux Stents and Standard DJ Stents in Children With Urolithiasis

Child, OnlyUrolithiasis
The Children's Hospital of Zhejiang University School of Medicine108 enrolled1 locationNCT06569173
Recruiting
Not Applicable

The Effect of Different Body Positions and Channel Sheaths on RIRS

Urolithiasis
The First Affiliated Hospital of Guangzhou Medical University120 enrolled1 locationNCT06438497