RecruitingPhase 4NCT07701967

Efficacy and Safety of Depemokimab Monotherapy Without Concomitant Use of Intranasal Corticosteroids (INCS) in Japanese Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

A Phase IV, Single-arm, Open-label Study to Evaluate the Efficacy and Safety of 100 mg SC Depemokimab Monotherapy Without Concomitant Use of Intranasal Corticosteroids (INCS) in Japanese Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Are Inadequately Controlled With Standard Treatment


Sponsor

GlaxoSmithKline

Enrollment

28 participants

Start Date

Jul 15, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study will evaluate the efficacy and safety of depemokimab (GSK3511294) without concomitant use of Intranasal corticosteroids (INCS) in participants with Chronic rhinosinusitis with nasal polyps (CRSwNP).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Depemokimab for people with nasal polyps. The study is currently recruiting participants at 10 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALDepemokimab

Participants will receive depemokimab.


Locations(10)

GSK Investigational Site

Ehime, Japan

GSK Investigational Site

Ehime, Japan

GSK Investigational Site

Fukui, Japan

GSK Investigational Site

Fukuoka, Japan

GSK Investigational Site

Gunma, Japan

GSK Investigational Site

Nagano, Japan

GSK Investigational Site

Osaka, Japan

GSK Investigational Site

Saitama, Japan

GSK Investigational Site

Shiga, Japan

GSK Investigational Site

Shizuoka, Japan

View Full Details on ClinicalTrials.gov

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NCT07701967


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