Triamcinolone Nanocapsules After Endoscopic Nasal Surgery
Clinical Evaluation of Triamcinolone Acetonide-loaded Nanoparticles For Nasal Postoperative Application
Deraya University
50 participants
May 1, 2026
INTERVENTIONAL
Conditions
Summary
This randomised, single-masked, parallel-group clinical trial will evaluate the efficacy and safety of a topical triamcinolone acetonide-loaded polymeric nanocapsule formulation for postoperative care following endoscopic nasal surgery. Participants will receive either the investigational triamcinolone acetonide-loaded nanocapsule formulation or standard normal saline nasal irrigation. Postoperative nasal healing, inflammation, patient-reported sinonasal symptoms, postoperative complications, and corticosteroid-related adverse effects will be compared between the two groups.
Eligibility
Plain Language Summary
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Interventions
Triamcinolone acetonide incorporated into polymeric nanocapsules prepared using a nanoprecipitation method will be administered topically to the postoperative nasal cavity.
Participants will receive postoperative nasal irrigation with 0.9% sodium chloride solution.
Locations(1)
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NCT07714525