Oxytocin in Postmenopausal Women
Circulating Oxytocin and Its Clinical Correlates in Postmenopausal Women Compared With Premenopausal Controls - The OxyMENO Study
University Hospital, Basel, Switzerland
30 participants
Aug 20, 2026
OBSERVATIONAL
Conditions
Summary
The aim of the present study is to assess whether cumulative endogenous neurophysin I secretion over one month differs between premenopausal and postmenopausal women. Using repeated measurements of neurophysin-I (NP-I, equimolar surrogate marker of oxytocin) across defined physiological time points, this study investigates oxytocin system regulation under cyclic and non-cyclic hormonal conditions. The primary hypothesis is that cumulative NP-I release, expressed as the area under the curve (AUC) is lower in the postmenopausal group compared to the premenopausal group.
Eligibility
Plain Language Summary
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Interventions
This study is an observational investigation involving repeated venous blood sampling and non-invasive clinical assessments ov four study visits.
Locations(1)
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NCT07742124