RecruitingNot ApplicableNCT07377383

Cardiometabolic Adaptations to Concurrent Training: Effect of Effort Configuration on Postmenopausal Women

Cardiometabolic Adaptations to Resistance and Endurance Exercise: Effects of Effort Configuration in Concurrent Training for Postmenopausal Women

Sponsor

Universidade da Coruña

Enrollment

60 participants

Start Date

May 5, 2026

Study Type

INTERVENTIONAL

Conditions

Postmenopausal Hypertension

Summary

The main objectives of this project are to assess the effects of a 20-week concurrent training program on neuromuscular adaptations, body composition, cardiometabolic health, quality of life, mood state, physical self-perception, and menopause-related symptoms in physically active postmenopausal women, and to compare the adaptations resulting from different combinations of endurance and resistance training programs with varying effort configurations. Additionally, this project aims to examine the longitudinal interaction and potential interference effects between endurance and resistance training effort configurations throughout the training program and to determine the optimal combination of effort configurations that maximizes health benefits in concurrent training programs for physically active postmenopausal women.

Eligibility

Sex: FEMALEMin Age: 46 YearsMax Age: 65 Years

Inclusion Criteria5

At least one year since the last menstrual period.
Physically active, defined as engaging in 150-300 minutes of moderate physical activity per week or at least 75 minutes of vigorous activity per week.
Three or fewer traditional cardiovascular risk factors.
Asymptomatic and without cardiovascular (except controlled hypertension), metabolic, or renal diseases.
In the case of hypertensive participants, well-controlled grade 1 hypertension managed with a single medication.

Exclusion Criteria4

Diagnosis of grade 2 or grade 3 hypertension.
Hypertension managed with more than one medication or with a drug that could interfere with cardiovascular responses to exercise (e.g., beta-blockers).
Current or prior use of hormone replacement therapy.
Hypertensive response to exercise.

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Interventions

OTHERConcurrent Training Program

All participants will follow a 20-week concurrent training program consisting of four supervised training sessions per week: two sessions of endurance training and two sessions of resistance training. Each resistance training session will include exercises targeting major muscle groups (leg press, bench press, prone leg curl, and lat pull-down). All exercises will be performed using the 12-repetition maximum load, completing a total of 36 repetitions per exercise. Inter-set rest periods will be arranged so that the total rest time per exercise is 6 minutes, maintaining a consistent work-to-rest ratio. Recovery between exercises will be 4 minutes. will consist of cycling exercises performed at prescribed intensities determined from incremental exercise testing. All sessions will have a total duration of thirty minutes. Work and recovery intervals will be arranged to maintain a consistent work-to-rest ratio across all participants.